Trust the Evidence

Trust the Evidence

Describe the intervention

The principles

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Carl Heneghan's avatar
Tom Jefferson and Carl Heneghan
Sep 02, 2025
∙ Paid

Recommendation 3: The intervention and placebo must be described in detail, together with adjuvants, delivery vehicles and excipients (if any)

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Acute Respiratory Infections (ARIs) are usually “will of the wisp” episodes; they are there one day and gone the next. If you produce a vaccine against an ARI, you are preparing something which is to be given to many people who do not have the disease. Your goal is to prevent disease and, even worse, its complications.

So you are asking people to take you on trust. In fact, it’s not people you’re targeting, but taxpayers. Trust is no longer a given after the recent reckless interventions in the Covid pandemic and the general climate of distrust which governments and public health bodies have managed to engineer.

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A cornerstone of trust is honesty, transparency. You trust a shopkeeper who tells you “this good is cheaper but not of high quality as this, which will last you a lifetime”.

Then the choice is yours and yours alone. 

Clearly, informing taxpa…

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