Trust the Evidence

Trust the Evidence

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Trust the Evidence
Trust the Evidence
Studies that Misled the World - No Serious Adverse Events
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Studies that Misled the World - No Serious Adverse Events

How two of the most cited published trials of oseltamivir misled the world

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Carl Heneghan
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Tom Jefferson
Apr 28, 2025
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Studies that Misled the World - No Serious Adverse Events
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In 2010, we met at New College in Oxford to discuss the methods of our updated and amalgamated review of antivirals.

The news of our upcoming update to the Cochrane review was circulating, catching the attention of various media outlets eager for a story. In light of this interest, we approached Roche with a request: could they release the data from the Kaiser et al. review? Our goal was to verify the review's findings and provide an adequate response to Hayashi’s comments.

The Story of Influenza Antivirals: Part 3

Carl Heneghan and Tom Jefferson
·
March 24, 2023
The Story of Influenza Antivirals: Part 3

We trundled along to 2009, when the world confronted the first influenza pandemic of the century.

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Unfortunately, Roche did not provide the requested data. Instead, they later characterised the media’s early involvement as evidence of a conspiracy against them. This response was particularly frustrating for us, as our only intention was to gain access to the data to update our review.

The next drama came in 2009 when Tom’s phone rang, and a voice said, “Hello, Dr Jefferson, I am the person who wrote the Treanor and Nicholson trials.”

The Story of Influenza Antivirals: Part 4

The Story of Influenza Antivirals: Part 4

Tom Jefferson and Carl Heneghan
·
March 28, 2023
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