Trust the Evidence

Trust the Evidence

UK Covid-19 Inquiry - Module 1: The resilience and preparedness of the United Kingdom

Chapter 4 An Effective Strategy

Carl Heneghan's avatar
Tom Jefferson's avatar
Carl Heneghan
and
Tom Jefferson
Aug 06, 2024
∙ Paid

In the words of the report: 

Share Trust the Evidence

Superficially, this looks clear and in logical order. 

Let’s start with the 2011 preparedness plan. The Inquiry correctly identifies the focus on a single pathogen (influenza) as one reason for its irrelevance. We would qualify that as the main reason, together with the underlying box thinking.

The UK 2011 plan was inspired by the US HHS Pandemic plan, which contained several “Critical assumptions.”

Specific assumptions for antiviral drugs include: “Treatment with a neuraminidase inhibitor (oseltamivir [Tamiflu®] or zanamivir [Relenza®]) will be effective in decreasing risk of pneumonia, will decrease hospitalization by about half (as shown for interpandemic influenza), and will also decrease mortality.”

The Hallett report fails to mention that the plan's essence was based on the mass use of antivirals (stockpiled at great public expense) to “hold the fort” until influenza pandemic vaccines became available. In the 2009 influenza pandemic, neither was needed an…

Keep reading with a 7-day free trial

Subscribe to Trust the Evidence to keep reading this post and get 7 days of free access to the full post archives.

Already a paid subscriber? Sign in
© 2025 Carl Heneghan
Privacy ∙ Terms ∙ Collection notice
Start your SubstackGet the app
Substack is the home for great culture