Trust the Evidence

Trust the Evidence

Share this post

Trust the Evidence
Trust the Evidence
Why Observational Studies shouldn’t be used to assess Respiratory Virus Interventions - Part 2
Copy link
Facebook
Email
Notes
More

Why Observational Studies shouldn’t be used to assess Respiratory Virus Interventions - Part 2

The Long Read

Tom Jefferson's avatar
Carl Heneghan's avatar
Tom Jefferson
and
Carl Heneghan
Feb 10, 2023
∙ Paid
40

Share this post

Trust the Evidence
Trust the Evidence
Why Observational Studies shouldn’t be used to assess Respiratory Virus Interventions - Part 2
Copy link
Facebook
Email
Notes
More
6
Share

Share

We have seen how past observational studies of the SARS-CoV-1 epidemic gave implausible effect estimates while randomised trials gave more conservative estimates. However, there are other reasons specific to respiratory viral transmission why observational designs should be used cautiously for informing policy.

Let’s try and put these in the context of t…

This post is for paid subscribers

Already a paid subscriber? Sign in
© 2025 Carl Heneghan
Privacy ∙ Terms ∙ Collection notice
Start writingGet the app
Substack is the home for great culture

Share

Copy link
Facebook
Email
Notes
More